WebcircHECTD1 facilitated the proliferation, migration, and invasion of GC cells. circHECTD1 enhances glutaminolysis in GC The effects of circHECTD1 on glutaminolysis were further explored. We ... WebcircHECTD1 in IS. qRT-PCR and western blot were used to test gene and protein expressions, respectively. CCK-8 assay was used to investigate the cell viability. Moreover, cell migration and tube formation were assessed by transwell and tube formation assays. In addition, RIP and luciferase assay were performed to explore the association among ...
circHECTD1 attenuates apoptosis of alveolar epithelial cells in …
WebMar 24, 2024 · Abstract. Purpose. The objective of this paper is to explore the role of circHECTD1 in vascular smooth muscle cells (VSMCs) and atherosclerosis (AS). … WebNov 27, 2024 · After exposure to SiO 2, the circHECTD1 level was decreased, which was associated with an increase in HECTD1 in HPF-a cells.SiO 2-induced autophagy was reversed by either circHECTD1 overexpression or HECTD1 knockdown in HPF-a cells, with restored SiO 2-induced fibroblast activation, proliferation, and migration via downstream … dwarf photo
circHECTD1 attenuates apoptosis of alveolar epithelial cells in acute
WebFeb 9, 2024 · Knockdown of circHECTD1 inhibited proliferation and invasion in vitro, and also reduced the growth of tumor and prolonged the prognosis in vivo. Knockdown of … WebSep 1, 2024 · The relationships between circHECTD1, miRNAs, and target genes were assessed by RNA pull-down, luciferase reporter gene, and RNA-FISH assays. circHECTD1 was downregulated in LPS-induced human and mouse AECs (HBE and MLE-12). The knockdown of circHECTD1 increased the apoptotic rates and the expressions of miR … WebNoticeably, circHectd1 was highly expressed in the brain tissue of mice and dramatically increased after tMCAO. To further validate our results, 37 plasma samples from AIS patients were detected with 34 age and gender matched healthy controls, the levels of circHECTD1 were significantly increased in AIS patients, suggesting that the level of ... dwarf photos